Lymphoma

Medical oncologist Sonali Smith, MD, a nationally known expert in lymphoma treatment and research, with patient Clayton Harris.

In the past few decades, tremendous strides have been made in the treatment of adult lymphomas — a group of blood cancers that begin in the white blood cells. Personalized and targeted therapies are resulting in higher success rates and patients surviving and thriving. Ongoing progress continues to offer hope and healing for patients facing this disease.

The University of Chicago Medicine has been at the forefront of this great move forward in lymphoma care. Here, the brightest minds in medicine work every day to advance the care of patients with lymphoma. Our lymphoma experts are committed to developing new therapies for this complex disease and bringing the latest treatments to our patients as quickly as possible. As one of the busiest lymphoma programs in Chicago, we manage care for thousands of patients and see approximately 250 new cases each year.

Specialized Care for High-Risk Lymphomas

Aggressive, high-grade non-Hodgkin lymphomas require prompt care from a team of experts. Our High-Risk Lymphoma Clinic provides focused care for or a variety of fast-growing lymphoma subtypes, including relapsed/refractory aggressive large B-cell lymphomas, Richter's syndrome, relapsed/refractory mantle cell lymphoma and peripheral T-cell lymphomas.

Why Choose Us for Lymphoma Care?

Top Diagnostic Expertise

Stem Cell Transplantation

We take an aggressive approach to treating lymphomas that return after initial treatment. In some cases, stem cell transplantation offers the best chance to cure patients with relapsed lymphoma. Many patients are candidates for outpatient stem cell transplant.

UChicago Medicine had the best one-year stem cell transplant outcomes in Chicago and the highest relative to predicted outcomes, according to recent annual reports from the Center for International Bone and Marrow Transplant Research. Learn about our stem cell transplant outcomes.

CAR T-cell Therapy for Non-Hodgkin Lymphoma

We were the first medical center in Illinois to offer CAR T-cell therapy, a breakthrough immunotherapy for the treatment of certain types of non-Hodgkin lymphoma and other blood cancers. CAR T-cell therapy supercharges the patient’s disease-fighting T-cells to find and destroy cancer cells. Many patients receive CAR T-cell therapy on an outpatient basis, enabling them to return to the comfort of their home in between treatments and appointments.

Specialized Care for Adolescents and Young Adults

Survivorship

Our supportive oncology program offers a full range of services, including mental health care, nutrition counseling, social work services and more.

We offer long-term follow-up and care for adults who were treated for lymphoma as adolescents or young adults. Patients receive an individualized survivorship plan to help them address any medical or psychosocial issues they experience as a result of cancer or its treatment.

Lymphoma Biobank

The Hoogland Lymphoma Biobank at UChicago Medicine is an innovative new program that links epidemiology (the study of how disease spreads and can be controlled) to malignant lymphoma tissue. The biobank collects and stores donated biospecimens (e.g. tissue, urine, blood) and connects it to personal and medical information. Biobank researchers will examine how lifestyle, occupation, environment and genes affect lymphoma. The goal of the program is to increase understanding of how to prevent, diagnose and treat lymphoma.

USNEWS Leukemia, Lymphoma & Myeloma badge 2024-2025

Top-Ranked Cancer Care and High Performing in Leukemia, Lymphoma and Myeloma

According to U.S. New & World Report's 2024-2025 rankings, UChicago Medicine is the top-ranked cancer hospital in Illinois and high performing in leukemia, lymphoma and myeloma care.

Learn more

Request an Appointment

We are currently experiencing a high volume of inquiries, leading to delayed response times. For faster assistance, please call 1-855-702-8222 to schedule your appointment.

If you have symptoms of an urgent nature, please call your doctor or go to the emergency room immediately.

For Referring Physicians

To refer a patient for lymphoma care, please call UCM Physician Connect at 1-800-824-2282.

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Wendy Stock, MD, talks with a patient in clinic

Cancer Care Second Opinions

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Participate in a Clinical Trial

UChicago Medicine lymphoma experts are actively conducting clinical trials of new and promising treatments.

Find a Clinical Trial

Supportive oncology team, including Chris Daugherty, MD

Helping You Cope With Cancer

Our Supportive Oncology program offers a range of services to support you and your family during your cancer treatment.

Supportive Oncology